Tuesday, January 30, 2007

Diabetic Neuropathy

Diabetic Neuropathy, a nerve disorder caused by diabetes, is characterized by a loss or reduction of sensation in the feet, and in some cases the hands, and pain and weakness in the feet. The symptoms of diabetic neuropathy vary. Numbness and tingling in feet are often the first sign. Some people notice no symptoms, while others are severely disabled. Neuropathy may cause both pain and insensitivity to pain in the same person. Conventional medicine offers little in the prevention or treatment of diabetic neuropathy, yet there is a great deal of information available which shows that the proper usage of dietary supplements can be of significant benefit.

Diabetes is associated with a fatty acid imbalance. In experimental models, essential fatty acid desaturation contributes to reductions in peripheral nerve conduction velocity and blood flow. This fatty acid imbalance may be corrected by dietary supplements that contain gamma-linolenic acid (GLA), such as borage oil.

Nerve conduction and perfusion deficits in diabetics have been corrected by a combination of antioxidant and gamma-linolenic acid (GLA) supplements.

Deficient and toxic neuropathies can be alleviated by improving lifestyle and dietary factors. The following combinations of nutritional supplements might be particularly effective:

1. Gamma-linolenic acid (GLA), Fish oil concentrate, and Ascorbyl palmitate offer a potential synergistic approach to correcting a fatty acid imbalance by enhancing blood flow to the nerves, and protecting against free radicals.

2. Vitamin B12 in the form of methylcobalamin, taken in lozenge form along with folic acid has been shown to correct many neurological diseases, including neuropathy.

3. Protect against free radicals and enhance neuronal energy metabolism by taking Alpha-Lipoic Acid (ALA), Acetyl-L-Carnitine, N-Acetyl Cysteine (NAC) and Vitamin C.

4. Taking a broad-spectrum Multinutrient(Vitamin & Mineral) formula can help suppress free radical injury to the nerves, while supplying supplemental amounts of folic acid and vitamin B12.

Diabetic Complications - Can Benfotiamine Help Prevent Them?

Diabetic complications contribute too many life threatening diseases globally. The root cause of diabetic complications is elevated glucose levels which contribute to blood vessel damage. Diabetic retinopathy, nephropathy, or neuropathy are caused by damage to small blood vessel in the eyes, nerves and kidneys, etc. The bottom line of this damage is the lowering of the life expectancy of millions of diabetics worldwide.

What Can Be Done About It?

Few therapies are available today that treat diabetic complications. Most healthcare professionals recommend that their patients monitor their blood sugar by taking several blood readings a day to determine the amount of sugar in their blood. Blood sugar readings are generally higher from one to two hours after a meal.

It is suggested by these professionals that keeping blood sugar readings as close to normal as possible will reduce the onset of diabetic complications. Research has shown that there are four, chemical pathways that lead to diabetic complications. Instead of trying to explain these rather difficult chemical pathways, let the reader understand that diabetic complications are mainly caused by excess sugar in the cells, a condition known by the term advanced glycation endproducts (AGE) formation.

The research that was released in 2003 by a team of researchers from the Albert Einstein Collage of Medicine opened the possibilities that it may be possible to actually prevent and/or contain diabetic complications such as retinopathy, neuropathy and heart/circulatory conditions brought about by the presence of advanced glycation endproducts.

What Did This Research Suggest?

The Einstein researchers’ work showed that a substance called, “benfotiamine”, could reduce the effects of AGE by increasing the amount of an enzyme called transketolase. The research indicated that transketolase was increased by 300% which was enough to make a serious reduction of three of the four chemical pathways that open the door for diabetic complications in terms of vascular damage in diabetics. This vascular damage is directly responsible for the diabetic complications such as neuropathy, retinopathy and heart/circulatory conditions that lead to heart attack and stroke.

Can Benfotaimine Be Considered A Prudent Preventative?

Current research suggests that benfotiamine could possibly reduce the chances of diabetics developing the aforementioned complications. Many healthcare professionals readily recommend patients to add this nutritional supplement to their toolkit in the battle to prevent these insidious conditions that shorten the lives of thousands of diabetics annually.

Where Can I Find More Information About Benfotiamine?

More information about benfotiamine can be found by visiting the web site below and following the links. These links will give the reader a good base to make an informed decision about the use of benfotiamine in the battle against diabetic complications brought about by the presence of advanced glycation endproducts (AGE) which is excess sugar in the blood.